Block of hERG K+ Channel by Classic Histamine H1 Receptor Antagonist Chlorpheniramine
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چکیده
منابع مشابه
Block of HERG k channel by classic histamine h(1) receptor antagonist chlorpheniramine.
Chlorpheniramine is a potent first-generation histamine H(1) receptor antagonist that can increase action potential duration and induce QT prolongation in several animal models. Since block of cardiac human ether-a-go-go-related gene (hERG) channels is one of leading causes of acquired long QT syndrome, we investigated the acute effects of chlorpheniramine on hERG channels to determine the elec...
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The role of histamine in the regulation of food and water intake in mammals and birds of the review, this study evaluated the effects of intraperitoneal administration of chlorpheniramine as histamine H1-receptor antagonist, in broiler chicks on feed intake and satiety in water and was hungry. 32 male Ross broiler chicks reared in groups of four weeks, 16 samples (control and test) were then in...
متن کاملEffects of chlorpheniramine (histamine H1 receptor antagonist) on food and water intake in broiler chickens in hunger and satiety
The role of histamine in the regulation of food and water intake in mammals and birds of the review, this study evaluated the effects of intraperitoneal administration of chlorpheniramine as histamine H1-receptor antagonist, in broiler chicks on feed intake and satiety in water and was hungry. 32 male Ross broiler chicks reared in groups of four weeks, 16 samples (control and test) were then in...
متن کاملeffects of chlorpheniramine (histamine h1 receptor antagonist) on food and water intake in broiler chickens in hunger and satiety
the role of histamine in the regulation of food and water intake in mammals and birds of the review, this study evaluated the effects of intraperitoneal administration of chlorpheniramine as histamine h1-receptor antagonist, in broiler chicks on feed intake and satiety in water and was hungry. 32 male ross broiler chicks reared in groups of four weeks, 16 samples (control and test) were then in...
متن کاملEffects of chlorpheniramine and hydroxyzine administration, as histamine H1- receptor antagonists, on the nociception threshold of cholestatic rats
Introduction: The elevated endogenous opioid tone in cholestasis is associated with changes including an increase in the nociception threshold. We aimed to study the effect of chlorpheniramine and hydroxyzine, H1-receptor antagonists, on modulation of nociception in a model of elevated endogenous opioid tone, cholestasis. Methods: Cholestasis was induced by ligation of main bile duct using ...
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ژورنال
عنوان ژورنال: The Korean Journal of Physiology and Pharmacology
سال: 2009
ISSN: 1226-4512
DOI: 10.4196/kjpp.2009.13.3.215